Investigation of Renal Histopathological Changes Due to HIV-RT Inhibitor 2-phenoxymethyl-5-chlorobenzimidazole Administration in Rats
| Autor: | AKBAY YARPUZLU, Ayşegül, UĞUR, Yeşim, NAZİKOĞLU, Ayşegül, ASAN, Esin, YİLDİZ, İlkay |
|---|---|
| Jazyk: | angličtina |
| Předmět: | |
| Zdroj: | Volume: 35, Issue: 1 25-30 Hacettepe Journal of Biology and Chemistry |
| ISSN: | 2687-475X |
| Popis: | Introduction2-Phenoxymethyl-5-chlorobenzimidazole is a substituted benzimidazole that has been synthesized by our team. Benzimidazoles and their substituted derivatives have been used as antimicrobials in the treatment of Pneumocystis pneumonia 1 , Helicobacter pylori 2 , in plant protection 3 , as antivirals against cytomegalovirus 4 , as well as antiparasitics against Giardia lamblia 5 and some Microsporidia species such as Encephalitozoon hellem and Encephalitozoon intestinalis 6 by binding to the cytoskeleton 7 . Some have also been shown to be inhibitors of HIV-RT 8 , and Adenosine Deaminase ADA 9 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|