Benzoik asit halkali yeni hibrit kalkonlarin sentezi ve biyolojik aktiviteleri
Autor: | KURŞUN AKTAR, Bedriye Seda, SICAK, Yusuf, ORUÇ-EMRE, Emine Elçin |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Volume: 6, Issue: 1 7-14 International Journal of Chemistry and Technology |
ISSN: | 2602-277X |
Popis: | A series of E-4-(3-oxo-3-(substituted)prop-1-en-1-yl)benzoic acid derivatives (1-5) were synthesized by the Claisen-Schmidt condensation of various ketones with 4-formylbenzoic acid. The anticholinesterase (AChE and BChE), tyrosinase, and urease inhibition activities of the synthesized compounds (1-5) were examined. It was found that the most active compound against AChE enzyme in anticholinesterase inhibition activity was compound 1. Compound 4 was the most active compound in tyrosinase inhibition activity, while compound 3 was the most active compound in urease psychological activity. |
Databáze: | OpenAIRE |
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