Benzoik asit halkali yeni hibrit kalkonlarin sentezi ve biyolojik aktiviteleri

Autor: KURŞUN AKTAR, Bedriye Seda, SICAK, Yusuf, ORUÇ-EMRE, Emine Elçin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Volume: 6, Issue: 1 7-14
International Journal of Chemistry and Technology
ISSN: 2602-277X
Popis: A series of E-4-(3-oxo-3-(substituted)prop-1-en-1-yl)benzoic acid derivatives (1-5) were synthesized by the Claisen-Schmidt condensation of various ketones with 4-formylbenzoic acid. The anticholinesterase (AChE and BChE), tyrosinase, and urease inhibition activities of the synthesized compounds (1-5) were examined. It was found that the most active compound against AChE enzyme in anticholinesterase inhibition activity was compound 1. Compound 4 was the most active compound in tyrosinase inhibition activity, while compound 3 was the most active compound in urease psychological activity.
Databáze: OpenAIRE