L-Carnitine treatment in a child with valproic acid intoxication

Autor: ARSLANOĞLU, Mehmet Özgür, KAÇMAZ, Ebru, BOZAN, Gürkan, DINLEYICI, Ener Cagri, ÖZKAN, Burak, SAHİN, Sabiha
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Volume: 3, Issue: 1 36-38
Eurasian Journal of Critical Care
ISSN: 2667-8721
Popis: With its growing application in neurological and psychiatric diseases, valproic acid overdose due to acute and chronic use has been causing emergency admission. Asymptomatic cases of hyperammonemia may be found in valproic acid poisoning ranging from central nervous system depression to coma. While supportive therapy is adequate, in most cases active charcoal, levocarnitine supplementation, and treatment with naloxane and hemodialysis, when needed, can also be used. In the case study reported in this paper, we aimed to focus at bringing awareness to the use of levocarnitine in asymptomatic patients with valproic acid poisoning accompanied by hyperammonemia.
Databáze: OpenAIRE