Erratum: Investigation of the Levels of Lipid Peroxidation (MDA), Antioxidant Substances (Glutathione, Ceruloplasmin) and Antioxidant Vitamins (β-carotene and Retinol) in the Experimental Pulmoner Fibrosis in Rats
| Autor: | ÇELİKEZEN, Fatih Çağlar, ERTEKİN, Ali |
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| Jazyk: | turečtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Volume: 32, Issue: 2 91-91 Van Veterinary Journal |
| ISSN: | 2149-3359 2149-8644 |
| Popis: | Bu çalışmada antineoplastik ajan olan bleomisinin bir komplikasyonu olarak şekillenen akciğer fibrosisinin, lipid peroksidasyon markeri malondialdehit (MDA), antioksidan maddeler redükte glutatyon (GSH) ve serüloplazmin ile antioksidan vitaminler β-karoten ve retinol seviyeleri üzerine etkileri araştırıldı. Çalışmada 15 Wistar- Albino ırkı erkek rat kullanıldı. Akciğer fibrosisini oluşturmak için bleomisin hidroklorid 7.5 mg/kg oranında tek doz intratrakeal olarak kullanıldı. Yapılan analizlerde, kontrol değerlere göre MDA seviyelerindeki artışlar istatistiksel olarak anlamsız bulunurken (p>0.05), β-karoten p The levels of MDA, antioxidant substances and antioxidant vitamins were studied on the experimental pulmonary fibrosis induced by a complication of bleomycine, an antineoplastic agent, in rats. In the study 15 male Wistar-Albino rats were used. The same animals values prior to the experimental treatment were considered as the control. To establish the experimental fibrosis, bleomycine hydrochloride was used intratraceally at a single dose of 7.5 mg / kg. After the fibrosis was performed, lipid peroxidation, antioxidant substances and vitamin analyses were carried out in the blood and serum. The levels of β-carotene, ceruloplasmin and retinol were found to be increased significantly (p0.005) as compared the control data. However a significant decrease in the GSH level was observed (p |
| Databáze: | OpenAIRE |
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