Increased fibrinogen levels at diagnosis are associated with adverse outcome in patients with acute myeloid leukemia
| Autor: | Berger MD Heini AD Seipel K Mueller B Angelillo-Scherrer A Pabst T. |
|---|---|
| Zdroj: | Hemat Oncol |
| Popis: | Increased plasma fibrinogen levels are associated with shortened overall survival (OS) in some solid tumor types. In contrast the prognostic significance of varying fibrinogen levels in acute myeloid leukemia (AML) at diagnosis is unknown. In this study we assessed the prognostic significance of fibrinogen levels in AML patients. In a comprehensive retrospective single center study we determined the survival rates of 375 consecutive AML patients undergoing at least one cycle of intensive chemotherapy induction treatment. Patients were dichotomized between low ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|