Variability of growth in children starting antiretroviral treatment in southern Africa

Autor: Gsponer T., Weigel R., Davies M. A., Bolton C., Moultrie H., Vaz P., Rabie H., Technau K., Ndirangu J., Eley B., Garone D., Wellington M., Giddy J., Ehmer J., Egger M., Keiser O., Ie D. E. A. Southern Africa
Rok vydání: 2013
Zdroj: Pediatrics
Popis: BACKGROUND: Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Malawi Zambia Zimbabwe Mozambique and South Africa. METHODS: Treatment naive children aged /= 1. For HAZ the corresponding range was 2.33 (95 CI: 2.62 to 2.02) to 1.27 (95 CI: 1.58 to 1.00) for baseline HAZ /= 1. CONCLUSIONS: Despite a sustained growth response and catch up growth in children with advanced HIV disease treated with ART normal weights and heights are not achieved over 3 years of ART.
Databáze: OpenAIRE