| Autor: |
Rajab, Nadia, Angel, Paul W, Kurowska-Stolarska, Mariola, Milling, Simon, Pacheco, Chris M, Rutar, Matt, Choi, Jarny, Wells, Christine A |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| DOI: |
10.1101/719237 |
| Popis: |
Summary Macrophages isolated from different tissues have distinct niche roles that maintain tissue homeostasis, as well as providing surveillance for tissue injury or infection. By assembling a large transcriptional atlas of human myeloid biology representing ∼1000 samples, we address the question of how well laboratory models, including pluripotent-derived cells, represent macrophage biology, and particularly whether these can model resident tissue macrophage specialisation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
