| Autor: |
Hare, Jonathan, Fiore-Gartland, Andrew, McGowan, Edward, Rosenthal, Rachel, Hunter, Eric, Gilmour, Jill, Nielsen, Morten |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Existing approaches to identifying predictive T-cell epitopes have traditionally utilized either 2-digit HLA super-families or more commonly autologous HLA alleles to facilitate the predictions, but frequently they may not consider their representation within a population. Here we propose a modification to this concept whereby subsets of individuals are selected for their specific HLA allele profiles and the representation they provide within a given population. Using this targeted approach to HLA selection and the linkages to specific individuals may enable the design of restricted experimental strategies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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