| Autor: |
Makanjuola, Samira, Okubena, Olajuwon, Ajonuma, Louis, Dosunmu, Adedoyin, Umukoro, Solomon, Erah, Patrick |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
The West-African variety ofSorghum bicolorleaf sheath (SBLS) Jobelyn®is a natural remedy,which has gained international recognition for its anti-anemic effect and energy boosting qualities in debilitating diseases.The widespread use of traditional medicine in the region usually confirms its safety, but not its efficacy or deep assessment of their pharmacological properties. The other major issue for herbal-based treatments is the lack of definite and complete information about the composition of the extracts.Despite limitations, efforts have been made in isolation and characterisation of active compounds in this specie ofsorghumshowing varioussubclasses of flavonoids including apigeninidin, a stable 3-deoxyanthocyanidin and potential fungal growth inhibitor, which accounts for 84% of the total extract.Non-clinical in vitro and in vivo studies support previous indications that this variety ofSorghum bicolorpossesses several biologically active compounds with potent antioxidant, anti-inflammatory, anti-aging and neuro-protective properties. Clinical studies show thatSBLS has the abilityto boosthemoglobin concentrations in anemic conditions and most remarkably to increase CD4 count in HIV-positive patients. The multiple effects and high safety profiles of this extract may encourage its development as a therapeutic agent for the treatment of anemia, chronic inflammatory conditions or in the symptomatic management of HIV infections.This review describesthe potential therapeutic aspectsof SBLS extractand its potential benefits. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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