Differential diagnosis between oral fibroma and inflammatory hyperplasia: a proposal for histopathological criteria

Autor: Badauy, Cristiano Macabu, Carrard, Vinícius Coelho, Nóbrega, Thaíse Gomes e, Nör, Felipe, Oliveira, Márcia Gaiger de, Sant'Ana Filho, Manoel
Přispěvatelé: CAPES
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Revista da Faculdade de Odontologia de Porto Alegre; v. 54, n. 1-3 (2013); 14-18
ISSN: 0566-1854
2177-0018
Popis: O presente estudo propôs critérios histopatológicos para o diagnóstico diferencial entre as entidades patológicas. Materiais e métodos: Cortes histológicos de lesões diagnosticadas microscopicamente como Fibroma Oral (n=61) e Hiperplasia Fibrosa Inflamatória (n=75) foram submetidos a diferentes técnicas de coloração (Hematoxilina-eosina, Tricrômio de Masson e Ácido Fosfomolibidico- Vermelho de Picrosírius) para permitir análises quantitativa e qualitativa. A análise qualitativa da densidade do colágeno foi baseada nas lâminas coradas em Hematoxilina- eosina e observada no centro e periferia de cada lesão. Resultados: Fibras colágenas enoveladas eram mais frequentes e mais densas no Fibroma Oral, enquanto as fibras paralelas eram observadas na Hiperplasia Fibrosa Inflamatória (teste exato de Fisher, p
Oral Fibroma and Inflammatory Hyperplasia display similarities in their clinical and histopathological appearance. The present study proposed histopathological criteria for the differential diagnosis between those pathological entities. Histological sections of lesions histopathologically diagnosed as Oral Fibroma (n=61) and Inflammatory Hyperplasia (n=75) and were submitted to different techniques (Hematoxylin-Eosin; Masson Trichrome and Phosphomolybdic acid - Picrosirius red) to allow quantitative and qualitative analysis. The qualitative analysis of collagen density was based on sections stained by Hematoxylin-Eosin and focused in the center and periphery of each lesion. Wound and collagen fibers were more frequent and higher in Oral Fibroma, while parallel fibers were more frequent in Inflammatory Hyperplasia (Fisher’s exact test, p
Databáze: OpenAIRE
Externí odkaz: