| Popis: |
The use of dryers is diverse - in the production of food products, the production of multi-tonne products of microbiological synthesis. The main advantage of using dryers for the manufacture of pharmaceutical substances is compliance with GMP requirements and the availability of validation documents. Such dryers are manufactured by such companies as GEA Niro Atomiae and Anhydro (Denmark) [1]. Dried products with promising raw materials are a good choice for restaurant business, especially fast food such as bistros and cafes. Consumers of these types of products are power structures, food concentrate production, special contingent (geologists, athletes, astronauts), etc. Spray drying, as well as freeze drying, is the most common method of obtaining microbiological synthesis products from native solutions, as it ensures drying of liquids within a few seconds [2]. Specifically, spray dryers are used to produce dry bacterial preparations, antibiotics, vaccines and other pharmaceutical products. This type of apparatus was first used in the early twentieth century to dry milk and blood. The principle of their operation is the fine spraying of solutions to be dried using spray discs or nozzles when the aerosol comes into contact with hot air in a special chamber [3]. This method of drying is based on the vacuum extraction of moisture from the material that is in a frozen state; in this case, the ice turns into a gas state, bypassing the liquid state [4]. A new promising type of lyophilic dryers is considered, in which Peltier thermoelectric elements are used for sublimation and desublimation. The principle of operation is described and basic information about spray-sublimation dryers for the preparation of powdered pharmaceutical substances for inhalation of dry powdered substances and their needleless intradermal injection is given. It is known that freeze dryers are used in production facilities for drying serums, antibiotics, enzymes, and food products. |
