Antifungal activity of L-homoserine O-acetyltransferase (CaMet2p) inhibitors

Autor: Gabriel, Iwona, Kuplińska, Aleksandra, Rząd, Kamila, Milewski, Sławomir
Rok vydání: 2022
Předmět:
DOI: 10.34808/jhc2-ad98
Popis: The dataset contains a set of optical densities at 600 nm measured at microplate reader to determine the rate of fungal growth in the presence of Candida albicans homoserine O-acetyltransferase inhibitors. Antifungal activities were determined against several strains from Candida spp. and others by the modified M27-A3 method specified by the CLSI. We used strains from cell culture collections (C. albicans ATCC 10231, C. parapsilosis ATCC 22019, C. krusei ATCC 6258, C. glabrata ATCC 90030, C. krusei ATCC 6258, C. famata DSM 3428, C. rugosa DSM 2031, C. dublinensis CBS 7987 and Saccharomyces cerevisiae ATCC 9763) as well as C. albicans clinical strains.The studies were financially supported from the project OPUS 20 financed by the National Science Centre (No. UMO-2020/39/B/NZ7/01519).
Databáze: OpenAIRE