Pertinent plasma indicators of the ability of chickens to synthesize and store lipids
| Autor: | Baéza, Elisabeth, Jégou, Maëva, Gondret, Florence, Lalande-Martin, J, Tea, I, Duval, Elisabeth, Berri, Cécile, Collin, Anne, Metayer-Coustard, Sonia, Louveau, Isabelle, Lagarrigue, Sandrine, Duclos, Michel Jacques |
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| Přispěvatelé: | Recherches Avicoles (SRA), Institut National de la Recherche Agronomique (INRA), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes - Faculté des Sciences et des Techniques, Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS), FatInteger. ANR-11-BSV7-0004, Unité de Recherches Avicoles (URA), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
métabolisme énergétique
chicken [SDV]Life Sciences [q-bio] Abdominal Fat poulet Fatty Acids Nonesterified métabolisme des lipides Diet High-Fat dépôt de gras lipids energy metabolism fat deposition plasma markers starch Animals Triglycerides animal en croissance amidon 3-Hydroxybutyric Acid Body Weight Lipid Metabolism Betaine Cholesterol Adipose Tissue Liver Body Composition marqueur plasmatique Chickens Biomarkers |
| Zdroj: | Journal of Animal Science Journal of Animal Science, American Society of Animal Science, 2015, 93 (1), pp.107-116. ⟨10.2527/jas.2014-8482⟩ Journal of Animal Science 1 (93), 107-116. (2015) |
| ISSN: | 0021-8812 1525-3163 |
| Popis: | Excessive deposition of body fat is detrimental to production efficiency. The aim of this study was to provide plasma indicators of chickens' ability to store fat. From 3 to 9 wk of age, chickens from 2 experimental lines exhibiting a 2.5-fold difference in abdominal fat content and fed experimental diets with contrasted feed energy sources were compared. The diets contained 80 vs. 20 g of lipids and 379 vs. 514 g of starch per kg of feed, respectively, but had the same ME and total protein contents. Cellulose was used to dilute energy in the high-fat diet. At 9 wk of age, the body composition was analyzed and blood samples were collected. A metabolome-wide approach based on proton nuclear magnetic resonance spectroscopy was associated with conventional measurements of plasma parameters. A metabolomics approach showed that betaine, glutamine, and histidine were the most discriminating metabolites between groups. Betaine, uric acid, triglycerides, and phospholipids were positively correlated (r > 0.3; P < 0.05) and glutamine, histidine, triiodothyronine, homocysteine, and β-hydroxybutyrate were negatively correlated (r < -0.3; P < 0.05) with relative weight of abdominal fat and/or fat situated at the top of external face of the thigh. The combination of plasma free fatty acids, total cholesterol, phospholipid, β-hydroxybutyrate, glutamine, and methionine levels accounted for 74% of the variability of the relative weight of abdominal fat. On the other hand, the combination of plasma triglyceride and homocysteine levels accounted for 37% of the variability of fat situated at the top of external face of the thigh. The variations in plasma levels of betaine, homocysteine, uric acid, glutamine, and histidine suggest the implication of methyl donors in the control of hepatic lipid synthesis and illustrate the interplay between AA, glucose, and lipid metabolisms in growing chickens. |
| Databáze: | OpenAIRE |
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