Contrasting patterns of nuclear and mtDNA diversity in Native American populations

Autor: Ning Ning, Yang, Stephane, Mazières, Claudio, Bravi, Nicolas, Ray, Sijia, Wang, Mari-Wyn, Burley, Gabriel, Bedoya, Winston, Rojas, Maria V, Parra, Julio A, Molina, Carla, Gallo, Giovanni, Poletti, Kim, Hill, Ana M, Hurtado, Maria L, Petzl-Erler, Luiza T, Tsuneto, William, Klitz, Ramiro, Barrantes, Elena, Llop, Francisco, Rothhammer, Damian, Labuda, Francisco M, Salzano, Maria-Cátira, Bortolini, Laurent, Excoffier, Jean Michel, Dugoujon, Andrés, Ruiz-Linares
Přispěvatelé: Dept of Genetics, Evolution and Environment [London] (UCL-GEE), University College of London [London] (UCL), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Instituto Multidisciplinario de Biología Celular [La Plata] (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Universidad Nacional de la Plata [Argentine] (UNLP)-Comisión de Investigaciones Científicas [Buenos Aires] (CIC), EnviroSPACE Laboratory - Forel Institute, Institute for Environmental Sciences [Geneva] (ISE), University of Geneva [Switzerland]-University of Geneva [Switzerland], Harvard FAS Center for Systems Biology, Laboratorio de Genética Molecular, Universidad de Antioquia = University of Antioquia [Medellín, Colombia], Centro de Investigaciones Biomédicas de Guatemala, School of Human Evolution and Social Change, Arizona State University [Tempe] (ASU), Departamento de Genética, Universidade Federal do Paraná (UFPR), Escuela de Biologia, Universidad Nacional de Costa Rica, Facultad de Medicina & Instituto de Alta Investigacion, Universidad de Tarapaca-Universidade de Chile, CHU Sainte-Justine, Département de Pédiatrie, Université de Montréal (UdeM), Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS)-Instituto de Biociencias, CMPG, University of Bern, Programme AMAZONIE - Analyse, modélisation et ingénierie des systèmes amazoniens (programme interdisciplinaire du CNRS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Annals of Human Genetics / Stories of Human Genetics
Annals of Human Genetics / Stories of Human Genetics, 2010, pp.74(6):525-38. ⟨10.1111/j.1469-1809.2010.00608.x⟩
Annals of Human Genetics, Vol. 74, No 6 (2010) pp. 525-38
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
ISSN: 0003-4800
Popis: We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions.
Instituto Multidisciplinario de Biología Celular
Databáze: OpenAIRE
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