Markers of bone metabolism during 14 days of bed rest in young and older men
| Autor: | Buehlmeier, J., Frings-Meuthen, P., Nina Mohorko, Lau, P., Mazzucco, S., Ferretti, J. L., Biolo, G., Pisot, R., Simunic, B., Rittweger, J. |
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| Přispěvatelé: | Buehlmeier, J�rn, Frings-Meuthen, P., Mohorko, N., Lau, P., Mazzucco, S., Ferretti, J. L., Biolo, G., Pisot, R., Simunic, B., Rittweger, J., Rauch, F |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Aging Time Factors Physiology Endocrinology Diabetes and Metabolism Wnt-signalling Middle Aged Diabetes and Metabolism Young Adult Immobilization Age effects Endocrinology Mechano-adaptation Age effect Countermeasure Humans Original Article Orthopedics and Sports Medicine Bone Remodeling Bone Resorption Bed Rest Biomarkers Weltraumphysiologie |
| Zdroj: | Scopus-Elsevier Journal of Musculoskeletal & Neuronal Interactions |
| Popis: | OBJECTIVE: We aimed at comparing markers of bone metabolism during unloading in young and older men, and to assess countermeasure effectiveness. METHODS: 16 older (60±2 years) and 8 younger men (23±3 years) underwent bed rest (BR) for 14 days. A subgroup of the Older performed cognitive training during BR and supplemented protein and potassium bicarbonate afterwards. Biochemical markers of bone and calcium/phosphate metabolism were assessed. RESULTS: At baseline urinary NTX and CTX were greater in younger than in older subjects (P0.17). P1NP was greater in young than in older subjects (P |
| Databáze: | OpenAIRE |
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