| Autor: |
Lan, Chen, Qi, Chen, Yue-Fang, Wang |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Zhongguo shi yan xue ye xue za zhi. 30(2) |
| ISSN: |
1009-2137 |
| Popis: |
To evaluate the prognosis value of average daily platelet amount increase in children with B-cell acute lymphoblastic leukemia(B-ALL) treated by CCCG-ALL-2015 regimen.106 children with primary B-ALL were retrospective analyzed, standardized MRD test protocol was used to detect the MRD level (19 d and 46 d) after chemotherapy. The platelet count was measured by Sysmex XE-2100. Kaplan-Meier survival curve statistics was used to analyze the event free survival(EFS) rate of the children.The trend of negative correlation existed between PPC and TPR (rAp can reflect the effect of B-ALL chemotherapy and can be used to monitor the curative effect and prognosis of B-ALL children.定量检测平均每日血小板增长量在B细胞急性淋巴细胞白血病患儿中的预后价值.评价平均每日血小板增长量(average daily platelet amount increase, Ap)在 CCCG-ALL-2015 方案治疗的B细胞急性淋巴细胞白血病（B-ALL）患儿预后中的价值.回顾性分析106例初发B-ALL患儿，标准化MRD检测方案检测化疗后d 19与d 46 MRD水平，Sysmex XE-2100检测血小板计数，Kaplan-Meier生存曲线分析患儿的无事件生存(EFS）率.相关性分析显示PPC和TPR呈负相关（rAp增生可反映B-ALL化疗效果，可用于B-ALL患儿疗效及预后的监测. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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