Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats
| Autor: | SORRENTINO, RAFFAELLA, D'EMMANUELE DI VILLA BIANCA, ROBERTA, Lippolis L, Sorrentino L, Autore G, Pinto A. |
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| Přispěvatelé: | Sorrentino, Raffaella, D'EMMANUELE DI VILLA BIANCA, Roberta, Lippolis, L, Sorrentino, L, Autore, G, Pinto, A. |
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
Lipopolysaccharides
Male Cromakalim LPS Potassium Channels Vasodilator Agents Aorta Thoracic Blood Pressure In Vitro Techniques Muscle Smooth Vascular Phenylephrine Adenosine Triphosphate L-NAME Heart Rate Glyburide Animals rat Enzyme Inhibitors Rats Wistar KATP channel arterial blood pressure Tetraethylammonium Rats NG-Nitroarginine Methyl Ester glibenclamide Papers Muscle Contraction |
| Popis: | We have investigated the role of ATP-sensitive potassium (K(ATP)) channels in an experimental model of a delayed phase of vascular hyporeactivity induced by lipopolysaccharide (LPS) in rats. After 24 h, from LPS treatment, in anaesthetized rats the bolus injection of phenylephrine (PE) produced an increase in mean arterial pressure (MAP) significantly (P |
| Databáze: | OpenAIRE |
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