fMRI findings in an aphasic patient with reversed cerebral dominance for language

Autor:	Vandervliet, Everhard J. M., Jo Verhoeven, Sebastiaan Engelborghs, Peter Paul De Deyn, Paul M. Parizel, Peter Marien
Přispěvatelé:	Clinical sciences, Neurology
Jazyk:	angličtina
Rok vydání:	2008
Předmět:	Medicine(all) Aged 80 and over Brain Mapping Brain/physiopathology Brain Cerebral Infarction Magnetic Resonance Imaging behavioral disciplines and activities Functional Laterality Aphasia Humans Female Human medicine Aphasia/physiopathology Cerebral Infarction/physiopathology Language
Zdroj:	Acta neurologica Belgica University of Western Australia
ISSN:	0300-9009
Popis:	An 80-year-old right-handed woman with no history of brain damage or familial strain of left-handedness acutely developed aphasia associated with a left hemiparesis following a right hemisphere stroke. Brain MRI showed a posterior insular ischemic infarction extending to the temporo-parietal region of the right hemisphere. Severe overall language disruption (global aphasia) in the acute phase of the stroke rapidly evolved into conduction aphasia, characterized by a neurolinguistic profile of disproportionately severe repetition deficits and markedly distorted phonological skills. In the lesion phase of the stroke, a functional MRI study using a word repetition task was conducted which revealed a consistent pattern of right hemisphere activations. For the first time, right hemisphere language dominance is demonstrated by fMRI in a clear instance of crossed aphasia in a dextral.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7cf6e669ca3b2d1fbcf9727f79a3e21 https://hdl.handle.net/10067/727930151162165141 Zobrazit plný text záznamu