Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Autor: Steeb, Theresa, Wessely, Anja, von Bubnoff, Dagmar, Dirschka, Thomas, Drexler, Konstantin, Falkenberg, Conrad, Hassel, Jessica C., Hayani, Kinan, Hüning, Svea, Kähler, Katharina C., Karrer, Sigrid, Krammer, Christian, Leiter, Ulrike, Lill, Diana, Marsela, Enklajd, Meiwes, Andreas, Nashan, Dorothée, Nasifoglu, Suzan, Schmitz, Lutz, Sirokay, Judith, Thiem, Alexander, Utikal, Jochen, Zink, Alexander, Berking, Carola, Heppt, Markus V.
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical Medicine, Vol 9, Iss 1438, p 1438 (2020)
Journal of Clinical Medicine
Volume 9
Issue 5
ISSN: 2077-0383
Popis: Patient-centered motives and expectations of the treatment of actinic keratoses (AK) have received little attention until now. Hence, we aimed to profile and cluster treatment motivations and expectations among patients with AK in a nationwide multicenter, cross-sectional study including patients from 14 German skin cancer centers. Patients were asked to complete a self-administered questionnaire. Treatment motives and expectations towards AK management were measured on a visual analogue scale from 1&ndash
10. Specific patient profiles were investigated with subgroup and correlation analysis. Overall, 403 patients were included. The highest motivation values were obtained for the items &ldquo
avoid transition to invasive squamous cell carcinoma&rdquo
(mean ±
standard deviation
8.98 ±
1.46), &ldquo
AK are considered precancerous lesions&rdquo
(8.72 ±
1.34) and &ldquo
treating physician recommends treatment&rdquo
(8.10 ±
2.37
p <
0.0001). The highest expectation values were observed for the items &ldquo
effective lesion clearance&rdquo
(8.36 ±
1.99), &ldquo
safety&rdquo
(8.20 ±
2.03) and &ldquo
treatment-related costs are covered by health insurance&rdquo
(8.00 ±
2.41
0.0001). Patients aged &ge
77 years and those with &ge
7 lesions were identified at high risk of not undergoing any treatment due to intrinsic and extrinsic motivation deficits. Heat mapping of correlation analysis revealed four clusters with distinct motivation and expectation profiles. This study provides a patient-based heuristic tool for a personalized treatment decision in patients with AK.
Databáze: OpenAIRE
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