[Chronic persistent HBsAg positive hepatitis in children. II. Effect of treatment with levamisole]
| Autor: | Masi, M, Paolucci, Paolo, Timoncini, G, Fantini, Mp, Chiodo, F, Franceschi, C. |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
B-Lymphocytes Hepatitis B Surface Antigens Rosette Formation Receptors Antigen B-Cell Alanine Transaminase Chronic persistent HBsAg positive hepatitis Effect of treatment with levamisole paediatric age Hepatitis B Levamisole Child Preschool Immunoglobulin G Lectins Chronic Disease Humans Female Aspartate Aminotransferases Child |
| Zdroj: | Bollettino dell'Istituto sieroterapico milanese. 57(4) |
| ISSN: | 0021-2547 |
| Popis: | In five children affected by HBsAg positive chronic persistent hepatitis a treatment with Levamisole (LMS) modified several immunological parameters which had been found altered before treatment. In particular the percentage of E rosette forming cells increased while that of EAC decreased; B lymphocytes with SmIgG and the responsiveness to phytohaemagglutinin, which were significantly decreased and increased respectively, got normal values. Since the persistence of HBsAg was unaffected by LMS treatment and a light increase of transaminase serum levels (GPT and GOT) was observed during treatment, doubts are expressed about the opportunity of using LMS in children affected by such a form of hepatitis. |
| Databáze: | OpenAIRE |
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