[Neurologic complications of infective endocarditis: do they have an impact on prognosis?]
| Autor: | Santiago Pigretti, María Cristina Zurrú, Aníbal Arias, Florencia Parcerisa, Ariel Luzzi, César Belziti |
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| Rok vydání: | 2017 |
| Předmět: |
lcsh:Immunologic diseases. Allergy
Aged 80 and over Male Brain Diseases neuroimaging disability evaluation infective endocarditis lcsh:R lcsh:Medicine Endocarditis Bacterial Middle Aged Prognosis mortality Magnetic Resonance Imaging cerebral ischemia lcsh:Infectious and parasitic diseases neurological manifestations Risk Factors Humans lcsh:RC109-216 Female Hospital Mortality Prospective Studies lcsh:RC581-607 Aged |
| Zdroj: | Medicina (Buenos Aires), Vol 77, Iss 2, Pp 89-94 (2017) |
| ISSN: | 0025-7680 |
| Popis: | Neurologic complications of infective endocarditis have been observed in 20-40% of cases. Our aim was to determine the frequency of neurologic involvement, clinical manifestations, lesional patterns and evolution in patients with infective endocarditis. This was a prospective cohort study. We included 98 patients with left-sided infective endocarditis. Forty seven percent presented neurologic involvement at some time of the disease. The frequency of symptoms was: focal deficit 61%, sensory disturbance 17% and seizures 2%, while 20% remain asymptomatic. The most prevailing lesion was cerebral ischemia (76%). Vegetations larger than 1 cm were associated to neurologic involvement (57% vs. 31%, p = 0.01). Valvular replacement was more common among patients with neurologic involvement (70% vs. 44%, p = 0.01). Hospital mortality was 20% in patients with neurologic manifestation versus 15% of those without it (p = 0.5). The length of stay was significantly prolonged in patients with neurologic affection (32 ± 27 vs. 21 ± 15 days, p = 0.01) and a favorable Rankin assessment at the discharge was less likely in patients with neurologic involvement (36% vs. 74%, p = 0.0001). In this cohort, the most frequent clinical manifestation was focal deficit and the most prevalent pattern of lesion was cerebral ischemia. Those with neurologic involvement presented an increased length of stay and more disability at the discharge but not statistical significant difference in hospital mortality. |
| Databáze: | OpenAIRE |
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