[Effect of pentoxifylline on the dissociation curve of oxyhemoglobin]

Autor:	GRANDILLO F, GIUNTA, Riccardo, SCOGNAMIGLIO G, TIRELLI, Armando, COPPOLA L, TORELLA R.
Přispěvatelé:	Grandillo, F, Giunta, Riccardo, Scognamiglio, G, Tirelli, Armando, Coppola, L, Torella, R.
Rok vydání:	1983
Předmět:	Male Oxygen Consumption Oxyhemoglobins Humans Theobromine Arterial Occlusive Diseases Female Pentoxifylline Aged
Zdroj:	Il Farmaco; edizione scientifica. 38(1)
ISSN:	0430-0920
Popis:	In 9 subjects with peripheral vascular insufficiencies the AA. have studied the behaviour of the oxyhaemoglobin dissociation curve before and after pentoxyphilline infusion. After this drug no variations were observed as it regards MCHC, 2-3-DPG and so on; however a positive correlation was found between 2-3-DPG and the Hill number. These results suggest that 2-3-DPG may influence the Hill number (which is the expression of the gradient of the oxyhaemoglobin dissociation curve) and therefore may interfere with O2 transport.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f458854a31ecc812f18ac716ff8a148e https://pubmed.ncbi.nlm.nih.gov/6825828 Zobrazit plný text záznamu