[Laser-induced fluorescence diagnosis of tumors exemplified by solid Ehrlich carcinoma]

Autor:	König K, Dietel W
Jazyk:	němčina
Rok vydání:	1990
Předmět:	Mice Inbred ICR Radiation-Sensitizing Agents Time Factors Ultraviolet Rays Lasers Fluorescence Hematoporphyrins Mice Spectrometry Fluorescence Animals Female Hematoporphyrin Derivative Carcinoma Ehrlich Tumor Neoplasm Transplantation
Zdroj:	Europe PubMed Central
ISSN:	0003-911X
Popis:	The laser-induced fluorescence of hematoporphyrin derivative (HpD) sensitized experimental Ehrlich carcinoma on mice is investigated. The fluorescence is excited with the 364-nm argon laser line. The tumor fluorescence spectra are recorded in the red spectral region. The HpD induced fluorescence of the tumors is superimposed on the autofluorescence of tissue. The tumor fluorescence shows a maximum 4 h after i.p. application of HpD. The fluorescence intensity is reduced by strong excitation causing bleaching of the HpD absorption. The fluorescence spectrum is also changing and the generation of a fluorescent photoproduct is observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f22e5f73a659bc012fe8a03b177b978f https://pubmed.ncbi.nlm.nih.gov/2138011 Zobrazit plný text záznamu