Is kidney function associated with cognition and mood in late life?
| Autor: | Tap, Lisanne, Corsonello, Andrea, Formiga, Francesc, Moreno-Gonzalez, Rafael, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ziere, Gijsbertus, Freiberger, Ellen, Sieber, Cornel, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Lainez Martinez, Sara, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, Mattace-Raso, Francesco |
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| Jazyk: | angličtina |
| Předmět: |
Aged
80 and over Male Research Depressive symptoms Kidney behavioral disciplines and activities Europe Cognition Cognitive impairment Older persons Chronic kidney disease Mood Activities of Daily Living Humans Female ddc:610 Estimated glomerular filtration rate Renal Insufficiency Chronic Aged Glomerular Filtration Rate |
| Zdroj: | BMC Geriatrics |
| ISSN: | 1471-2318 |
| DOI: | 10.1186/s12877-020-01707-4 |
| Popis: | Background Chronic kidney disease (CKD), cognitive impairment and depression share common risk factors. Previous studies did not investigate the possible association between kidney function and cognitive and mood disorders in older persons in a broad range of kidney function. The present study explored associations between kidney function, cognition and mood in outpatients of 75 years and over. Methods Baseline data of 2252 participants of the SCOPE study, an international multicenter cohort observational study,were used in which community-dwelling persons of 75 years and over were enrolled to screen for CKD Kidney function was estimated with the BIS1-eGFR equation, cognition was assessed with the Mini-Mental State Examination (MMSE) and mood with the Geriatric Depression Scale 15 items (GDS-15). Characteristics were compared across stages of CKD. Mean eGFR values were also compared across categories of MMSE ( 5/≤5). Results In total, 63% of the population had an eGFR |
| Databáze: | OpenAIRE |
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