[Localization of the gene coding for adenine phosphoribosyltransferase on the genetic map of chromosome 8 in the mouse]

Autor: Tatyana Nesterova, Pm, Borodin, Sm, Zakiian
Předmět:
Zdroj: Europe PubMed Central
Popis: Polymorphism of electrophoretic mobility of adenine phosphoribosyltransferase (APRT) was found in a population of domestic mice, Mus musculus bactrianus. The Aprt gene was mapped using two markers: plasma esterase 1 coded by the gene Es-1 situated at the distance of 26 morgans from the centromere, and a Robertsonian translocation Rb (8.17) 1 Iem which marks the centromere. The results of linkage analysis permitted to localize the gene Aprt at 51 morgans from the centromere, and 25 morgans distal from the gene Es-1 on the genetic map of chromosome 8. It is found that emotional stress does not alter the recombination rate at chromosome 8, when spermatocytes are at the pachytene stage.
Databáze: OpenAIRE