Voltage during atrial fibrillation is superior to voltage during sinus rhythm in localizing areas of delayed enhancement on magnetic resonance imaging: An assessment of the posterior left atrium in patients with persistent atrial fibrillation
| Autor: | Qureshi, N, Kim, S, Cantwell, C, Afonso, V, Bai, WJ, Ali, R, Shun-Shin, M, Louisa, M-L, Luther, V, Leong, K, Lim, E, Wright, I, Nagy, S, Hayat, S, Ng, FS, Koa-Wing, M, Linton, N, Lefroy, D, Whinnett, Z, Davies, DW, Kanagaratnam, P, Peters, N, Lim, PB |
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| Přispěvatelé: | British Heart Foundation, Rosetrees Trust, Imperial College Healthcare NHS Trust- BRC Funding, Wellcome Trust, Hansen Medical, Inc, St Jude Medical UK Ltd, Medical Research Council (MRC) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Cardiac & Cardiovascular Systems ROTORS Magnetic Resonance Imaging Cine Article Magnetic resonance imaging 0903 Biomedical Engineering Humans Heart Atria Atrial fibrillation voltage Correlation of Data 1102 Cardiorespiratory Medicine and Haematology Science & Technology LESIONS ASSOCIATION QUANTIFICATION Atrial fibrosis Middle Aged Atrial fibrillation Fibrosis SCAR Cardiovascular System & Hematology Cardiovascular System & Cardiology Catheter Ablation Female TACHYCARDIA Electrophysiologic Techniques Cardiac Life Sciences & Biomedicine INTEGRATION MRI |
| Zdroj: | Heart Rhythm |
| ISSN: | 1556-3871 1547-5271 |
| Popis: | Background Bipolar electrogram voltage during sinus rhythm (VSR) has been used as a surrogate for atrial fibrosis in guiding catheter ablation of persistent atrial fibrillation (AF), but the fixed rate and wavefront characteristics present during sinus rhythm may not accurately reflect underlying functional vulnerabilities responsible for AF maintenance. Objective The purpose of this study was determine whether, given adequate temporal sampling, the spatial distribution of mean AF voltage (VmAF) better correlates with delayed-enhancement magnetic resonance imaging (MRI-DE)–detected atrial fibrosis than VSR. Methods AF was mapped (8 seconds) during index ablation for persistent AF (20 patients) using a 20-pole catheter (660 ± 28 points/map). After cardioversion, VSR was mapped (557 ± 326 points/map). Electroanatomic and MRI-DE maps were co-registered in 14 patients. Results The time course of VmAF was assessed from 1–40 AF cycles (∼8 seconds) at 1113 locations. VmAF stabilized with sampling >4 seconds (mean voltage error 0.05 mV). Paired point analysis of VmAF from segments acquired 30 seconds apart (3667 sites; 15 patients) showed strong correlation (r = 0.95; P |
| Databáze: | OpenAIRE |
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