Management of Phrenic Stimulation in CRT Patients over the Long Term: Still an Unmet Need ?

Autor: Mauro, Biffi, Matteo, Bertini, Matteo, Ziacchi, Beatrice, Gardini, Andrea, Mazzotti, Giulia, Massaro, Igor, Diemberger, Cristian, Martignani, Cinzia, Valzania, Giuseppe, Boriani
Přispěvatelé: Biffi M, Bertini M, Ziacchi M, Gardini B, Mazzotti A, Massaro G, Diemberger I, Martignani C, Valzania C, Boriani G.
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Popis: Background: Phrenic stimulation (PS) may cause intolerable symptoms and prevent CRT delivery in 2-5% of patients. We sought to ensure effective cardiac resynchronization therapy (CRT) delivery by management of PS at the left ventricular (LV) target site. Methods and Results: Two hundred and eleven consecutive patients received a CRT device despite PS occurrence at the LV target site at implantation, when a PS-LV difference >2V was achieved by LV stimulation programming (cathode, pacing vector). PS management strategy both at implantation and at follow-up (FU) aimed to keep the target LV implantation site. LV reverse remodeling was assessed by echocardiography before implantation and at follow-up. LV lead placement was lateral/posterolateral in all the 211 patients; 51 of 211 had detectable PS at FU, 26 of 211 (12.3%) were symptomatic. Symptoms occurred more frequently when PS-LV difference was 3V is achieved. Further improvement in lead manufacturing and pacing electronics are awaited to meet this clinical need
Databáze: OpenAIRE