Interchangeability between 24-hour collection and single spot urines for vanillylmandelic and homovanillic acid levels in the diagnosis of neuroblastoma

Autor:	Cangemi, G, Barco, S, Reggiardo, G, Viscardi, E, DI CATALDO, Andrea, Garaventa, A, Melioli, G, Conte, M.
Rok vydání:	2013
Předmět:	Male Time Factors Infant Homovanillic Acid vanillylmandelic acid Urinalysis 24-hour collection Neuroblastoma Vanilmandelic Acid Child Preschool Biomarkers Tumor homovanillic acid neuroblastoma single spot urine Humans Female Child
Zdroj:	Pediatric bloodcancer. 60(12)
ISSN:	1545-5017
Popis:	The determination of the two urinary catecholamine metabolites homovanillic acid (HVA) and vanillylmandelic acid (VMA) is of crucial importance for the diagnosis and follow-up of neuroblastoma (NB). The standard practice for their measurement requires the use of 24-hour collections that are time consuming and difficult to obtain. In this article, we directly demonstrate that 24-hour collections and single spot urines are interchangeable for the determination of HVA and VMA expressed as ratio on creatinine concentration. This study can be useful for a faster management of NB at onset.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de1ebb26479ec4c6f55cccc87ce3995f https://pubmed.ncbi.nlm.nih.gov/23813598 Zobrazit plný text záznamu Plný text