| Popis: |
Fibrillary glomerulonephritis (FGN) and immunotactoid nephropathy (ITN) are diseases diagnosed only by electron microscopy. Until recently, information on the diseases has reached as reports on some cases. Much information, including the authors' observations, has been presently gathered so as there is a chance of attempting to pool and analyze it. It is quite obvious that investigators do not agree to evaluate FGN and ITN. Some authors are inclined to believe that these are one disease and propose to use the general term "fibrillary-immunotactoid nephropathy", we, like others, consider FGN and ITN as two different diseases. Our findings suggest that there are two diseases (FGN and ITN). We provide support for the data available in the literature on that the deposits are polyclonal in FGN and monoclonal in ITN. It is most likely that no sharp distinction can be made between FGN and ITN from the diameter of microtubules making up deposits (less or more than 30 nm); the procedure of their package and, to be sure, their chemical composition are of importance in establishing the diagnosis. |
