Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: optimizing health in preparation for adult life
| Autor: | Bamford, A., Turkova, A., Lyall, H., Foster, C., Klein, N., Bastiaans, D., Burger, D., Bernadi, S., Butler, K., Chiappini, E., Clayden, P., Della Negra, M., Giacomet, V., Giaquinto, C., Gibb, D., Galli, L., Hainaut, M., Koros, M., Marques, L., Nastouli, E., Niehues, T., Noguera-Julian, A., Rojo, P., Rudin, C., Scherpbier, H. J., Tudor-Williams, G., Welch, S. B. |
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| Přispěvatelé: | AII - Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology, AII - Infectious diseases |
| Rok vydání: | 2018 |
| Předmět: |
Male
Science et gestion hospitalières antiretroviral therapy Adolescent Pharmacologie Santé publique Humans Pharmacology (medical) Preschool Pathologie maladies infectieuses child Original Research Acquired Immunodeficiency Syndrome AIDS-Related Opportunistic Infections HIV-1 Coinfection Health Policy HIV‐1 Anti-Retroviral Agents Child Child Preschool Europe Female Infant Infant Newborn Infectious Diseases Newborn |
| Zdroj: | HIV MEDICINE r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname HIV medicine, 19(1), e1-e42. Wiley-Blackwell r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu HIV Medicine HIV medicine, 19 (1 |
| ISSN: | 1464-2662 |
| Popis: | The 2015 Paediatric European Network for Treatment of AIDS (PENTA) guidelines provide practical recommendations on the management of HIV-1 infection in children in Europe and are an update to those published in 2009. Aims of treatment have progressed significantly over the last decade, moving far beyond limitation of short-term morbidity and mortality to optimizing health status for adult life and minimizing the impact of chronic HIV infection on immune system development and health in general. Additionally, there is a greater need for increased awareness and minimization of long-term drug toxicity. The main updates to the previous guidelines include: an increase in the number of indications for antiretroviral therapy (ART) at all ages (higher CD4 thresholds for consideration of ART initiation and additional clinical indications), revised guidance on first- and second-line ART recommendations, including more recently available drug classes, expanded guidance on management of coinfections (including tuberculosis, hepatitis B and hepatitis C) and additional emphasis on the needs of adolescents as they approach transition to adult services. There is a new section on the current ART ‘pipeline’ of drug development, a comprehensive summary table of currently recommended ART with dosing recommendations. Differences between PENTA and current US and World Health Organization guidelines are highlighted and explained. SCOPUS: ar.j info:eu-repo/semantics/published |
| Databáze: | OpenAIRE |
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