Long-Lasting Partial Regression of Glioblastoma Multiforme Achieved by Edotecarin: Case Report

Autor:	Eduard, Vrdoljak, Marijo, Boban, Zana, Saratlija-Novaković, Josipa, Jović
Jazyk:	angličtina
Rok vydání:	2006
Předmět:	topoisomerase I inhibitor edotecarin recurring glioblastoma glioblastoma multiforme Indoles Adolescent Brain Neoplasms Carbazoles Humans Antineoplastic Agents Female Case Report Topoisomerase I Inhibitors Glioblastoma Combined Modality Therapy
Zdroj:	Croatian Medical Journal Volume 47 Issue 2
ISSN:	1332-8166 0353-9504
Popis:	We describe the response to a new chemotherapy agent, topoisomerase I inhibitor edotecarin in an 18-year-old woman with recurring glioblastoma. The therapy was administered for 17 months. The radiological partial response and clinical improvement have been achieved, with minor toxicity. Median survival of patients with glioblastoma is 10 months. With edotecarin we have achieved promising result, which should encourage further investigations to develop more efficient therapy for such a deadly disease.
Databáze:	OpenAIRE
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