| Autor: |
Vt, Ivanova, Kurochkina IaE, Ei, Burtseva, Ta, Oskerko, Sv, Trushakova, Es, Shevchenko, Eg, Cherkasov, Mikhail Shchelkanov, Ro, Matiushina, Lv, Kolobukhina, El, Feodoritova, An, Slepushkin |
| Předmět: |
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| Zdroj: |
Europe PubMed Central |
| Popis: |
The epidemic upsurge of influenza morbidity in the 2006-2007 season in Russia was caused by the active circulation of influenza A(H1N1), A(H3N2) and B viruses. The Center for Ecology and Epidemiology of Influenza studied 259 epidemic strains; All the strains were isolated on MDCK cell cultures. Influenza A(H1N1) viruses (n = 101) were antigenic variants of the references A/New Caledonia/20/99 and A/Solomon Islands/3/06. Influenza A(H3N2) viruses (n = 98) were antigenic variants of the references A/California/7/07 and A/Wisconsin/67/05. Twenty four influenza B virus strains were drift variants of the reference BI Shanghai/361/02 - lineage B/Yamagata/16188 and 36 were related to A/Malaysia/2506/05 - lineage B/Victoria/2/87). All the isolated strains actively interacted with human erythrocytes of the blood groups 0(I) and A(II) and very slightly with chicken ones. Twenty-two (48%) A(H1N1) strains and 19 (35%) A(H3N2) strains which were resistant to rimantafine were revealed. Studies of the donor sera collected in Moscow and the Moscow Region, the Jewish Autonomous Region, and Primorye revealed antibodies to today's strains; the level of antibodies in the preepidemic period depended on the region and strain. A study of changes in antibody formation in different periods of an epidemic process showed a rise in antibodies mainly to influenza A and B virus strains circulating in this period. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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