Thrombolytic Therapy Up-regulates Inflammatory Mediators Compared to Percutaneous Coronary Intervention (PCI)

Autor:	Garjani, A., Sohrabi, B., Aliakbar Movassaghpour, Andalib, S., Shokri, M., Taherkhanchi, B., Bagheri, B.
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Male Inflammation Percutaneous coronary interventions lcsh:R lcsh:Medicine Reperfusion therapy Middle Aged Toll-like receptor 4 Up-Regulation Percutaneous Coronary Intervention ST elevation myocardial infarction Humans Female Streptokinase Thrombolytic Therapy Inflammation Mediators Aged
Zdroj:	Iranian Journal of Allergy, Asthma and Immunology, Vol 15, Iss 4 (2016) Scopus-Elsevier
ISSN:	1735-5249 1735-1502
Popis:	The important role of reperfusion therapies in the treatment of acute myocardial infarction is well documented. However, reperfusion therapies can initiate inflammatory response and may damage the myocardium. The purpose of current study was to compare the effects of percutaneous coronary intervention and thrombolytic therapy on inflammatory markers in the setting of ST elevation myocardial infarction (STEMI). Eighty three patients with STEMI were enrolled in this study. 40 patients underwent percutaneous coronary intervention (PCI), and 43 patients received streptokinase (1.5 million IU) as a main medical reperfusion therapy. Monocyte expression of Toll-like receptor 4 (TLR4), serum levels of TNF-α and IL-1β, red cell distribution width (RDW) and C- reactive protein (CRP) were compared between groups at admission time, two hours and four hours after termination of treatment. p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d682c75c30dbec4df26c3dd5a3583300 https://ijaai.tums.ac.ir/index.php/ijaai/article/view/708 Zobrazit plný text záznamu Plný text ve formátu PDF