Improvement of Overactive Bladder Symptoms and Bladder Ischemia with Dutasteride in Patients with Benign Prostatic Enlargement

Autor: Naoki, Wada, Seiji, Matsumoto, Masafumi, Kita, Kazumi, Hashizume, Hidehiro, Kakizaki
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Lower urinary tract symptoms. 7(1):37-41
ISSN: 1757-5664
Popis: OBJECTIVES: To evaluate the correlation of clinical and urodynamic parameters with bladder vascular resistance before and after dutasteride treatment in patients with lower urinary tract symptoms associated with benign prostatic enlargement. METHODS: A prospective study was conducted in 30 consecutive patients with benign prostatic enlargement who had not been satisfied with alpha-adrenergic antagonist monotherapy. Before and 24 weeks after dutasteride add-on treatment, we assessed International Prostate Symptom Score (IPSS), prostate volume (PV), urodynamic study and contrast-enhanced color Doppler ultrasonography to measure bladder vascular resistive index (RI). RESULTS: Twenty-four weeks after dutasteride, PV significantly decreased from 68 ± 29 to 48 ± 28 mL (P
Databáze: OpenAIRE
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