Improvement of Overactive Bladder Symptoms and Bladder Ischemia with Dutasteride in Patients with Benign Prostatic Enlargement
Autor: | Naoki, Wada, Seiji, Matsumoto, Masafumi, Kita, Kazumi, Hashizume, Hidehiro, Kakizaki |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Aged
80 and over Male benign prostatic hyperplasia dutasteride Urinary Bladder Overactive Urinary Bladder Prostatic Hyperplasia Middle Aged bladder ischemia 5-alpha Reductase Inhibitors Treatment Outcome Ischemia Humans Drug Therapy Combination overactive bladder Prospective Studies lower urinary tract symptoms Adrenergic alpha-Antagonists Aged |
Zdroj: | Lower urinary tract symptoms. 7(1):37-41 |
ISSN: | 1757-5664 |
Popis: | OBJECTIVES: To evaluate the correlation of clinical and urodynamic parameters with bladder vascular resistance before and after dutasteride treatment in patients with lower urinary tract symptoms associated with benign prostatic enlargement. METHODS: A prospective study was conducted in 30 consecutive patients with benign prostatic enlargement who had not been satisfied with alpha-adrenergic antagonist monotherapy. Before and 24 weeks after dutasteride add-on treatment, we assessed International Prostate Symptom Score (IPSS), prostate volume (PV), urodynamic study and contrast-enhanced color Doppler ultrasonography to measure bladder vascular resistive index (RI). RESULTS: Twenty-four weeks after dutasteride, PV significantly decreased from 68 ± 29 to 48 ± 28 mL (P |
Databáze: | OpenAIRE |
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