Safety of anastomoses in colorectal cancer surgery in octogenarians: a prospective cohort study with propensity score matching
| Autor: | Lehmann, Kai S., Klinger, Carsten, Diers, Johannes, Buhr, Heinz-Johannes, Germer, Christoph-Thomas, Wiegering, Armin |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | BJS Open |
| ISSN: | 2474-9842 |
| Popis: | Background Up to 20 per cent of all operations for patients with colorectal cancer (CRC) are performed in octogenarians. Anastomotic leakage is a leading cause of morbidity and death after resection for CRC. The aim of this study was to assess the rate of anastomosis creation, the risk of anastomotic leakage and death in surgery for left-sided CRC in elderly patients. Methods This prospective cohort study compared patients less than 80 and 80 or more years with left-sided CRC resection performed between 2013 and 2019. Data were provided from a risk-adjusted surgical quality-assessment system with 219 participating centres in Germany. Outcome measures were the rate of anastomoses, anastomotic leakages, death at 30 days and 2-year overall survival (OS). Propensity score matching was used to control for selection bias and compare subgroups of patients of less than 80 and 80 or more years. Results Out of 18 959 patients, some 3169 (16.7 per cent) were octogenarians. Octogenarians were less likely to receive anastomoses (82.0 versus 92.9 per cent, P The aim of this study was to assess the impact of age of 80 years or older on the creation of anastomoses, the risk of anastomotic leakage and death in surgery for left-sided colorectal cancer. The authors found that anastomotic leakage is not more common in octogenarians, but age of 80 years or older is an independent factor for not receiving an anastomosis in surgery for left-sided colorectal cancer. Death in the case of leakage is disproportionately high at 16 per cent in octogenarians, which should be addressed in shared decision making. |
| Databáze: | OpenAIRE |
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