Pilot study of a multi-pronged intervention using social norms and priming to improve adherence to antiretroviral therapy and retention in care among adults living with HIV in Tanzania
| Autor: | McCoy, Sandra I., Fahey, Carolyn, Rao, Aarthi, Kapologwe, Ntuli, Njau, Prosper F., Bautista-Arredondo, Sergio |
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| Přispěvatelé: | Genberg, Becky L |
| Rok vydání: | 2017 |
| Předmět: |
RNA viruses
Male Pediatric AIDS lcsh:Medicine Social Sciences HIV Infections Pilot Projects Pathology and Laboratory Medicine Tanzania Trees Geographical Locations Immunodeficiency Viruses Medicine and Health Sciences Psychology Public and Occupational Health lcsh:Science Pediatric Surveillance Plants Middle Aged Vaccination and Immunization Infectious Diseases Mental Health Medical Microbiology Research Design Viral Pathogens Viruses HIV/AIDS Female Pathogens Behavioral and Social Aspects of Health Infection Research Article Adult Anti-HIV Agents General Science & Technology Immunology HIV prevention Antiretroviral Therapy Research and Analysis Methods Microbiology Young Adult Antiviral Therapy Clinical Research Retroviruses Behavioral and Social Science Humans Microbial Pathogens Prevention lcsh:R Lentivirus Organisms Cognitive Psychology Biology and Life Sciences HIV Pilot Studies Priming (Psychology) Patient Acceptance of Health Care Cost Effectiveness Research People and Places Africa Cognitive Science Patient Compliance lcsh:Q Preventive Medicine Neuroscience |
| Zdroj: | PloS one, vol 12, iss 5 PLoS ONE PLoS ONE, Vol 12, Iss 5, p e0177394 (2017) |
| Popis: | BackgroundInterventions incorporating constructs from behavioral economics and psychology have the potential to enhance HIV 'treatment as prevention' (TasP) strategies. To test this hypothesis, we evaluated an intervention to improve antiretroviral therapy (ART) adherence based on the concepts of social norms and priming.MethodsWe used tools from marketing research and patient-centered design to develop a combination intervention that included visual feedback about clinic-level retention in care, a self-relevant prime, and useful take-home items with the priming image. The intervention was implemented at two HIV primary clinics in Shinyanga, Tanzania in 2-week intervals for six months. We conducted a quasi-experimental pilot study with a random sample of exposed and unexposed adult patients living with HIV infection (PLHIV) to compare retention and the proportion of patients with medication possession ratio (MPR) ≥95% after six months. Intervention acceptability was determined with a convenience sample of 405 PLHIV at baseline (n = 189) and endline (n = 216).ResultsMedical records were reviewed for 438 PLHIV (320 intervention, 118 standard of care). In adjusted analyses, PLHIV exposed to the intervention were significantly more likely to be in care after 6 months (87% vs. 79%, adjusted odds ratio (ORa) = 1.73, 95% CI: 1.08, 2.78, p |
| Databáze: | OpenAIRE |
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