Autor: |
Md, Rekhter, Iv, Andrianova, Se, Ragimov, Er, Andreeva, Aa, Mironov, Em, Tararak, Alexander Orekhov |
Předmět: |
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Zdroj: |
Europe PubMed Central |
Popis: |
Balloon catheter de-endothelialization of abdominal aorta of cholesterol-fed rabbits was performed. As a result, partly endothelialized neointima was formed, consisting of smooth muscle cells and macrophages. Neutral lipids stored more intensely in non-endothelialized part of neointima. Preferential intracellular lipid accumulation in this area was observed while predominantly extracellular lipid accumulation was found in endothelium-covered part of neointima. It is supposed that endothelium inhibits intracellular lipid accumulation and at the same time stimulates an extracellular one, but as a whole it reduces the density of lipid inclusions in neointima. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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