Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection

Autor:	Last, Anna R, Roberts, Chrissy H, Cassama, Eunice, Nabicassa, Meno, Molina-Gonzalez, Sandra, Burr, Sarah E, Mabey, David CW, Bailey, Robin L, Holland, Martin J
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	Adult Aged 80 and over Male Trachoma Adolescent Virulence Chlamydiology and Rickettsiology Gene Dosage Infant Chlamydia trachomatis Middle Aged Severity of Illness Index Bacterial Load Young Adult Child Preschool Humans Female Child Aged Plasmids
Zdroj:	Journal of Clinical Microbiology
ISSN:	1098-660X 0095-1137
Popis:	The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with C. trachomatis load or disease severity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cd4abaea4e09cfa7af43377fb60bf6ab http://europepmc.org/articles/PMC3911420 Zobrazit plný text záznamu