Cerebrospinal fluid samples from patients with various neurological disorders have a transmissible cytotoxic activity with similar properties

Autor:	Beretti, Francesca, Pietrosemoli, Paola, Bartoletti, Anna Maria, Rondini, Ilaria, Portolani, Marinella
Rok vydání:	2006
Předmět:	Adult Male Protein Folding Adolescent Middle Aged Brain Ischemia Aged Animals Cytopathogenic Effect Viral Female Humans Nervous System Diseases Vero Cells Chlorocebus aethiops Viral Cytopathogenic Effect
Zdroj:	The new microbiologica. 29(2)
ISSN:	1121-7138
Popis:	When inoculated into cell cultures to search for cytopathic viruses, six out of 384 cerebrospinal fluid (CSF) samples from patients with different neurological disorders proved to have a transmissible cytotoxic activity (TCA) not correlated to a conventional infectious agents. Properties shown by a TCA previously detected in the CSF sample of a patient with brain ischemia (Portolani et al., 2005) were shared by each of the newly isolated TCAs. We conclude that independently of the neurological clinical picture shown by the patient, the TCA detected in the CSF samples under study could have the same origin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c99068b3d999553420a4fbfe0b602e0d https://pubmed.ncbi.nlm.nih.gov/16841556 Zobrazit plný text záznamu