Natural history of gastro-entero-pancreatic and thoracic neuroendocrine tumors. Data from a large prospective and retrospective Italian epidemiological study: the NET management study
| Autor: | Faggiano A., Ferolla P., Grimaldi F., Manzoni M., Davì M. V., Bianchi A., Valcavi R., Papini E., Giuffrida D., Ferone D., Fanciulli G., Arnaldi G., Franchi G. M., Francia G., Fasola G., Crino L., Pontecorvi A., Colao A., CAMPANA, DAVIDE, TOMASSETTI, PAOLA |
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| Přispěvatelé: | Faggiano, A, Ferolla, P, Grimaldi, F, Campana, D, Manzoni, M, Davì, Mv, Bianchi, A, Valcavi, R, Papini, E, Giuffrida, D, Ferone, D, Fanciulli, G, Arnaldi, G, Franchi, Gm, Francia, G, Fasola, G, Crino, L, Pontecorvi, A, Tomassetti, P, Colao, Annamaria, Faggiano A., Ferolla P., Grimaldi F., Campana D., Manzoni M., Davì M.V., Bianchi A., Valcavi R., Papini E., Giuffrida D., Ferone D., Fanciulli G., Arnaldi G., Franchi G.M., Francia G., Fasola G., Crino L., Pontecorvi A., Tomassetti P., Colao A. |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male epidemiology neuroendocrine tumors risk factors survival Adolescent THORACIC NEUROENDOCRINE TUMORS Young Adult NET MANAGEMENT STUDY Stomach Neoplasms Intestinal Neoplasms GASTRO ENTERO PANCREATIC ITALIAN EPIDEMIOLOGY STUDY Multiple Endocrine Neoplasia Type 1 Prevalence Humans Prospective Studies Child Aged Retrospective Studies Aged 80 and over Disease Management Infant Settore MED/13 - ENDOCRINOLOGIA Middle Aged Thoracic Neoplasms Prognosis Pancreatic Neoplasms Survival Rate Neuroendocrine Tumors Italy Child Preschool Female |
| Zdroj: | Journal of endocrinological investigation. 35(9) |
| ISSN: | 1720-8386 |
| Popis: | BACKGROUND: The few epidemiological data available in literature on neuroendocrine tumors (NET) are mainly based on Registry databases, missing therefore details on their clinical and natural history. AIM: To investigate epidemiology, clinical presentation, and natural history of NET. DESIGN AND SETTING: A large national retrospective survey was conducted in 13 Italian referral centers. Among 1203 NET, 820 originating in the thorax (T-NET), in the gastro-enteropancreatic tract (GEP-NET) or metastatic NET of unknown primary origin (U-NET) were enrolled in the study. RESULTS: 93% had a sporadic and 7% a multiple endocrine neoplasia type 1 (MEN1)-associated tumor; 63% were GEP-NET, 33% T-NET, 4% U-NET. Pancreas and lung were the commonest primary sites. Poorly differentiated carcinomas were |
| Databáze: | OpenAIRE |
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