| Autor: |
Ml, Maestro Las Casas, Mª Teresa Sanz-Casla, del Barco V, Moreno J, Zanna I, Redondo E, Fernández C, Izquierdo L, Resel Estévez L |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
Europe PubMed Central |
| ISSN: |
0004-0614 |
| Popis: |
To determine the loss of heterozygosity (LOH) on 9p21 (locus D9S1747) in patients with renal carcinoma by analysis of microsatellite polymorphisms.40 patients with sporadic renal cancer were studied. LOH on 9p21 was performed by analysis of microsatellite polymorphisms.23.7% showed LOH on 9p21. No correlation was found between this genetic alteration and tumor features.LOH on 9p21 was found in 23.7% of the patients in this series. LOH was found in 26.9% of renal cell carcinomas, 25% of papillary carcinomas and 25% of Bellini duct carcinomas. LOH was not found in the other histological types. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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