Fibrillar ultrastructure of the glomerular basement membrane of the rat kidney as revealed by digestive treatment
| Autor: | Ichiyasu, Akira, Takaoka, Michio, Makino, Hirofumi, Takahashi, Kayo, Ota, Zensuke |
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| Rok vydání: | 1987 |
| Předmět: |
Pancreatic Elastase
urogenital system Kidney Glomerulus type IV collagen fibrillar ultrastructure Rats Inbred Strains urologic and male genital diseases female genital diseases and pregnancy complications Basement Membrane Rats Microscopy Electron glomerular basement membrane enzymatic digestion Animals Collagen alpha-Amylases |
| Zdroj: | Acta medica Okayama. 41(4) |
| ISSN: | 0386-300X |
| Popis: | Rat kidney glomerular basement membrane (GBM) was isolated and digested with alpha-amylase and elastase. Electron microscopy revealed a meshwork structure composed of fibrils 3 nm in width. They appeared to be type IV collagen fibrils. We succeeded in clarifying a significant ultrastructural aspect of the GBM which had been unclear until now. The findings are consistent with our previously proposed GBM molecular sieve theory. |
| Databáze: | OpenAIRE |
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