Occupational hypersensitivity pneumonitis in a baker: a new cause
| Autor: | Gerfaud-Valentin , Mathieu, Reboux , Gabriel, Traclet , Julie, Thivolet-Béjui , Françoise, Cordier , Jean-François, Cottin , Vincent |
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| Přispěvatelé: | Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), Centre national référent cancers rares - mésothéliomes malins pleuraux et tumeurs péritonéales rares ( MESOPATH ), CHU Caen-Hôpital côte de nacre, Hôpital Louis Pradel [CHU - HCL], Hospices Civils de Lyon ( HCL ), Centre de Référence des Maladies Pulmonaires Rares [Hôpital Louis Pradel - HCL], Hospices Civils de Lyon ( HCL ) -Hospices Civils de Lyon ( HCL ), Department of Pneumology [Lyon], Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Registre Multicentrique à Vocation Nationale des Mésothéliomes Pleuraux (MESONAT), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Hospices Civils de Lyon (HCL), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL) |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
MESH: Occupational Diseases MESH : Alveolitis Extrinsic Allergic MESH: Alveolitis Extrinsic Allergic [ SDV.EE.SANT ] Life Sciences [q-bio]/Ecology environment/Health MESH: Bread Humans MESH : Female Cooking [SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/Health MESH: Humans fungi MESH : Humans food and beverages MESH: Adult MESH: Cooking Bread MESH : Occupational Diseases MESH : Adult respiratory tract diseases Occupational Diseases MESH : Cooking Female MESH: Female MESH : Bread Alveolitis Extrinsic Allergic |
| Zdroj: | Chest Chest, American College of Chest Physicians, 2014, 145 (4), pp.856-8 |
| ISSN: | 0012-3692 |
| Popis: | International audience; Bakers are exposed daily to flour and may be susceptible to immunologic occupational diseases. A 30-year-old, nonsmoking, female baker was referred for progressive dyspnea on exertion, basal crackles on auscultation, restrictive lung function, decreased diffusing capacity of the lung for carbon monoxide, ground glass hyperdensities with a mosaic pattern on high-resolution CT scan, 25% lymphocytosis by BAL, and cellular chronic bronchiolitis with peribronchiolar interstitial inflammation by lung biopsy specimen. Cultures from flours isolated nine species, including Aspergillus fumigatus. Twenty-six antigens were tested. Serum-specific precipitins were found against A fumigatus, the flour mite Acarus siro, and total extracts from maize and oat. Outcome was favorable with cessation of occupational exposure to flours and transient therapy with prednisone and immunosuppressive agents. To our knowledge, this report is the first of a well-documented case of hypersensitivity pneumonitis due to sensitization to fungi- and mite-contaminated flours. Hypersensitivity pneumonitis--and not only asthma and allergic rhinitis--should be suspected in bakers with respiratory symptoms. |
| Databáze: | OpenAIRE |
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