[Cryptococcus where they are not expected: Five case reports of extra-cerebral and extra-pulmonary cryptococcosis]
| Autor: | Cazorla, Arnault, Alanio, Alexandre, Bretagne, Stéphane, Polivka, Marc, Shaar-Chneker, Caroline, Kaci, Rachid, Brouland, Jean-Philippe, Chretien, Fabrice, Jouvion, Grégory |
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| Přispěvatelé: | Service de pathologie, Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire (CNRMA), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Parasitologie-Mycologie [CHU Saint Louis, Paris], Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Mycologie moléculaire, Histopathologie humaine et Modèles animaux, Institut Pasteur [Paris], Laboratoire de Neuropathologie, Centre Hospitalier Sainte Anne, Université Paris Descartes - Paris 5 (UPD5), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), AP-HP Hôpital Lariboisière [Paris], Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire ( CNRMA ), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Parasitologie-Mycologie [Paris], Assistance publique - Hôpitaux de Paris (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Université Paris Descartes - Paris 5 ( UPD5 ), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Sacrum Discitis Cryptococcal Biopsy [SDV]Life Sciences [q-bio] Liver Abscess Extrapulmonaire Meningitis Cryptococcal Hepatitis B Chronic [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology Dermatomycoses Humans Meningitis Chronic Extracérébral Lymphatic Diseases [ SDV.MP.MYC ] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology Retrospective Studies [ SDV ] Life Sciences [q-bio] AIDS-Related Opportunistic Infections Immunohistochimie Cryptococcosis Hepatitis B Immunohistochemistry Extra-cerebral Cryptococcus Organ Specificity Extra-pulmonary [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Annales de Pathologie Annales de Pathologie, Elsevier Masson, 2015, 35 (6), pp.479--485. ⟨10.1016/j.annpat.2015.10.001⟩ Annales de Pathologie, 2015, 35 (6), pp.479--485. ⟨10.1016/j.annpat.2015.10.001⟩ Annales de Pathologie, Elsevier Masson, 2015, 35 (6), pp.479--485. 〈10.1016/j.annpat.2015.10.001〉 |
| ISSN: | 0242-6498 |
| DOI: | 10.1016/j.annpat.2015.10.001⟩ |
| Popis: | International audience; Cryptococcosis is a serious infection, possibly lethal, of worldwide distribution. It mainly affects immunosuppressed patients resulting with pulmonary and/or meningeal involvements or disseminated infections. Due to the rarity of visceral and osseous infections, and to the absence of specific clinical symptoms, this diagnosis is often deferred. Resulting of diagnostic errors, samples are often directed to the department of pathology and more rarely to the department of mycology. Histopathological examination appears crucial, highlighting encapsulated yeasts with alcian blue staining. Once the diagnosis is performed, an appropriate antifungal therapy must be quickly introduced because these infections are associated with a high mortality rate. The aim of our work was to report five extra-cerebral and extra-pulmonary cryptococcosis cases, to describe their histopathological features, to evoke diagnostic techniques and to discuss the differential diagnoses. |
| Databáze: | OpenAIRE |
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