Somatosensory, motor, and reaching/grasping responses to direct electrical stimulation of the human cingulate motor areas
| Autor: | Chassagnon, Serge, Minotti, Lorella, Kremer, Stéphane, Hoffmann, Dominique, Kahane, Philippe |
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| Přispěvatelé: | Deransart, Colin, Département de neurologie, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Service de médecine nucléaire [Strasbourg], CHU Strasbourg, Département de neurochirurgie, Collaboration |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Adolescent Epilepsy Frontal Lobe MESH: Monitoring Intraoperative MESH: Evoked Potentials Motor Gyrus Cinguli MESH: Motor Cortex MESH: Somatosensory Cortex MESH: Epilepsy Frontal Lobe Monitoring Intraoperative MESH: Child MESH: Gyrus Cinguli Humans [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] Child MESH: Brain Mapping MESH: Treatment Outcome MESH: Adolescent Brain Mapping MESH: Humans MESH: Middle Aged Hand Strength Motor Cortex MESH: Electric Stimulation MESH: Adult Somatosensory Cortex Middle Aged Evoked Potentials Motor Electric Stimulation MESH: Male Electrodes Implanted Treatment Outcome MESH: Hand Strength Female MESH: Electrodes Implanted [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] MESH: Female |
| Zdroj: | Journal of Neurosurgery Journal of Neurosurgery, American Association of Neurological Surgeons, 2008, 109 (4), pp.593-604. ⟨10.3171/JNS/2008/109/10/0593⟩ |
| ISSN: | 0022-3085 |
| DOI: | 10.3171/JNS/2008/109/10/0593⟩ |
| Popis: | International audience; OBJECT: Surgery for frontal lobe drug-resistant epilepsies is often limited by the apparent widespread distribution of the epileptogenic zone. Recent advances in the parcellation of the medial premotor cortex give the opportunity to reconsider "seizures of the supplementary motor area" (SMA), and to assess the contribution of cingulate motor areas (CMAs), SMA proper (SMAp), and pre-SMA to the symptomatology of premotor seizures. METHODS: The authors reviewed the results of extraoperative electrical stimulation (ES) applied in 52 candidates for epilepsy surgery who underwent stereotactic intracerebral electroencephalographic recordings, focusing on ES of the different medial premotor fields; that is, the anterior and posterior CMA, the SMAp, and the pre-SMA. The ES sites were localized by superposition of the postoperative lateral skull x-ray and the preoperative sagittal MR imaging studies. RESULTS: Among 94 electrodes reaching the medial premotor wall, 57 responses were obtained from the anterior CMA (13 cases), the posterior CMA (11), the pre-SMA (18), and the SMAp (15). The ES of the pre-SMA and SMAp gave rise most often to a combination of motor (31 cases), speech-related (22), or somatosensory (3) elementary symptoms. The ES of the CMA yielded simple (17 of 24) more often than complex responses (7 of 24), among which sensory symptoms (7) were overrepresented. Irrepressible exploratory reaching/grasping movements were elicited at the vicinity of the cingulate sulcus, from the anterior CMA (3 cases) or the pre-SMA (1). Clinical responses to ES were not predictive of the postoperative neurological outcome. CONCLUSIONS: These findings might be helpful in epilepsy surgery candidates, to better target investigation of the CMA, pre-SMA, and SMAp, and therefore to provide a better understanding of premotor seizures. |
| Databáze: | OpenAIRE |
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