Intravenous propafenone for suppression of symptomatic atrial fibrillation and atrial flutter in a first aid hospital
| Autor: | Liguori, A., Di Ieso, N., D Armiento, F. P., Furia, L., Claudio Napoli, Bruzzese, G., Piatto, A., Varriale, A. |
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| Přispěvatelé: | Liguori, A, DI IESO, N, D'Armiento, Fp, Furia, L, Napoli, Claudio, Bruzzese, G, Piatto, A, Varriale, A., di Ieso, N, D'Armiento, FRANCESCO PAOLO, Napoli, C |
| Jazyk: | angličtina |
| Rok vydání: | 1992 |
| Předmět: | |
| Zdroj: | Scopus-Elsevier |
| Popis: | The efficacy and safety of propafenone (PPF) were prospectively evaluated in 20 patients (13 men and 7 women, age 39 +/- 14 years) with atrial arrhythmias (AA) (atrial fibrillation: n = 13; atrial flutter: n = 7). All patients had arrhythmias from 109 +/- 63 minutes, (iT) without clinical evidence of heart failure. Intravenous PPF was given as a 1 mg/kg bolus over 5 minutes, with a therapeutical possibility of a second bolus (1 mg/kg) after 10 minutes if sinus rhythm was not restored. The conversion time (cT) was 6.4 +/- 2.2 minutes (range 3 to 18 minutes). In 19 patients (95%) sinus rhythm was restored and no serious adverse and proarrhythmic effects were noted in each patient. We conclude that 1) PPF is effective and acted significantly faster in controlling AA; 2) PPF appears to be well tolerated and relative safe with a low incidence of adverse and proarrhythmic effects in patients in a first aid station. |
| Databáze: | OpenAIRE |
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