[c-fos Gene expression during emotional stress in rats: blocking by delta sleep-inducing peptide]

Autor:	Kv, Sudakov, Pavel Umriukhin, Ev, Koplik, Kv, Anokhin
Rok vydání:	2000
Předmět:	Male Immobilization Delta Sleep-Inducing Peptide Hypothalamus Animals Gene Expression Septum of Brain Rats Wistar Amygdala Immunohistochemistry Proto-Oncogene Proteins c-fos Stress Psychological Rats
Zdroj:	Europe PubMed Central
ISSN:	0869-8139
Popis:	An emotional stress induces an obvious immediate early gene c-fos expression in the brain limbic structures in the rats predisposed to emotional stress. Administration of the delta-sleep-inducing peptide (DSIP) was shown to inhibit the c-fos expression. It led to an obvious inhibition of the c-fos expression in paraventricular nuclei of the hypothalamus, medial and lateral parts of the septum of rats predisposed to emotional stress. This mechanism seems to play an important role in the DSIP anti-stress effects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b90fd62ef69c81ae26c07ed5c348a479 https://pubmed.ncbi.nlm.nih.gov/10955299 Zobrazit plný text záznamu