Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness
| Autor: | Hervais-Adelman, Alexis, Legrand, Lore B, Zhan, Minye, Tamietto, Marco, de Gelder, Beatrice, Pegna, Alan J |
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| Přispěvatelé: | Cognitive Neuropsychology, University of Zurich, Pegna, Alan J, Cognitive Neuroscience, RS: FPN CN 10 |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
2805 Cognitive Neuroscience
Posterior parietal Vision Cognitive Neuroscience Movement VISUAL RESPONSE PROPERTIES 2804 Cellular and Molecular Neuroscience CINGULATE CORTEX Striate cortex MT/V5 blindsight cortical blindness fMRI hemianopia looming motion Human brain STRIATE CORTEX Visual response properties Cellular and Molecular Neuroscience 2809 Sensory Systems Motion Hemianopia ddc:150 Fmri VENTRAL INTRAPARIETAL AREA MOVEMENT VISION Ventral intraparietal area Original Research 10093 Institute of Psychology Cingulate cortex HUMAN BRAIN Blindsight Sensory Systems humanities ddc:616.8 Lateral geniculate nucleus POSTERIOR PARIETAL LATERAL GENICULATE-NUCLEUS 150 Psychology Looming Mt/v5 Cortical blindness Neuroscience |
| Zdroj: | Frontiers in Integrative Neuroscience Frontiers in Integrative Neuroscience, Vol. 9 (2015) P. 51 Frontiers in Integrative Neuroscience, 9:51. Frontiers Media S.A. |
| ISSN: | 1662-5145 |
| Popis: | Fast and automatic behavioral responses are required to avoid collision with an approaching stimulus. Accordingly, looming stimuli have been found to be highly salient and efficient attractors of attention due to the implication of potential collision and potential threat. Here, we address the question of whether looming motion is processed in the absence of any functional primary visual cortex and consequently without awareness. For this, we investigated a patient (TN) suffering from complete, bilateral damage to his primary visual cortex. Using an fMRI paradigm, we measured TN's brain activation during the presentation of looming, receding, rotating, and static point lights, of which he was unaware. When contrasted with other conditions, looming was found to produce bilateral activation of the middle temporal areas, as well as the superior temporal sulcus and inferior parietal lobe (IPL). The latter are generally thought to be involved in multisensory processing of motion in extrapersonal space, as well as attentional capture and saliency. No activity was found close to the lesioned V1 area. This demonstrates that looming motion is processed in the absence of awareness through direct subcortical projections to areas involved in multisensory processing of motion and saliency that bypass V-1. |
| Databáze: | OpenAIRE |
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