Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: usefulness of intraoperative radiological guidance. The Stereoplan
| Autor: | Derrey, Stéphane, Maltête, David, Chastan, Nathalie, Debono, Bertrand, Proust, François, Gérardin, Emmanuel, Weber, Jacques, Mihout, Bruno, Fréger, Pierre |
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| Přispěvatelé: | Service de neurochirurgie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Service de neurologie [Rouen], Normandie Université (NU)-Normandie Université (NU), Service de neurophysiologie [Rouen], Service de neurochirurgie, Clinique des cèdres, Service d'imagerie médicale [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Breton, Céline, Hôpital Charles Nicolle [Rouen], Normandie Université (NU)-Normandie Université (NU)-CHU Rouen |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Deep Brain Stimulation MESH: Monitoring Intraoperative MESH: Stereotaxic Techniques MESH: Magnetic Resonance Imaging Stereotaxic Techniques Subthalamic Nucleus Monitoring Intraoperative Humans [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] Prospective Studies Aged MESH: Subthalamic Nucleus MESH: Aged MESH: Humans MESH: Middle Aged Parkinson Disease MESH: Adult Middle Aged Magnetic Resonance Imaging MESH: Prospective Studies MESH: Male Radiography Female [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] MESH: Deep Brain Stimulation MESH: Female MESH: Parkinson Disease |
| Zdroj: | Stereotactic and Functional Neurosurgery Stereotactic and Functional Neurosurgery, Karger, 2008, 86 (6), pp.351-8. ⟨10.1159/000163556⟩ Stereotactic and Functional Neurosurgery, 2008, 86 (6), pp.351-8. ⟨10.1159/000163556⟩ |
| ISSN: | 1011-6125 1423-0372 |
| DOI: | 10.1159/000163556⟩ |
| Popis: | International audience; BACKGROUND: In our stereotactic procedure, intraoperative radiological documentation of electrode localization is performed using the Stereoplan. The aim of the study was to evaluate its accuracy. PATIENTS AND METHODS: Data of 20 consecutive patients, treated for Parkinson's disease by implantation of deep brain stimulators into the subthalamic nucleus, were collected prospectively. During surgery, Stereoplan coordinates of the tip of the central macroelectrodes were compared with intended coordinates along the central trajectory at 4 levels: (1) 10 mm above the anatomical target, (2) in the target, (3) in the substantia nigra pars reticulata, and (4) at the depth of contact 1. Before the frame's removal, Stereoplan coordinates of the contacts of the definitive electrode were compared with postoperative MRI coordinates. The mean of the differences was calculated in the x-, y-, and z-axis. Clinical results at 6 months were recorded. RESULTS: The mean of the differences between Stereoplan coordinates and intended coordinates for the macroelectrodes was lower than 1 mm. A submillimeter difference was also found for the definitive contacts. At 6 months, the Unified Parkinson's Disease Rating Scale III score improved by 70.6% compared with the baseline score. Dyskinesia and motor fluctuations decreased by 85.7 and 87%, respectively (p < 0.0001). CONCLUSION: Stereoplan could be considered an accurate intraoperative radiological system which assures the correct position of the electrode in the anatomical target. |
| Databáze: | OpenAIRE |
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