Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease
| Autor: | Weir-McCall, Jonathan R., Duce, Suzanne L., Gandy, Stephen J., Matthew, Shona Z., Martin, Patricia, Cassidy, Deirdre B., McCormick, Lynne, Belch, Jill J. F., Struthers, Allan D., Colhoun, Helen M., Houston, J. Graeme |
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| Jazyk: | angličtina |
| Předmět: |
Male
Atheroma burden Atherosclerosis Cerebrovascular disease Coronary artery disease Peripheral arterial disease Whole body magnetic resonance angiography Atheroma burden Age Factors Middle Aged Atherosclerosis Coronary artery disease Magnetic Resonance Imaging Cardiovascular Diseases Risk Factors Radiology Nuclear Medicine and imaging Peripheral arterial disease Humans Regression Analysis Female Whole Body Imaging cardiovascular diseases Cerebrovascular disease Whole body magnetic resonance angiography Research Article Aged |
| Zdroj: | BMC Medical Imaging Weir-McCall, J R, Duce, S L, Gandy, S J, Matthew, S Z, Martin, P, Cassidy, D B, McCormick, L, Belch, J J F, Struthers, A D, Colhoun, H M & Houston, J G 2016, ' Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease ', BMC medical imaging, vol. 16, no. 1 . https://doi.org/10.1186/s12880-016-0121-4 |
| ISSN: | 1471-2342 |
| DOI: | 10.1186/s12880-016-0121-4 |
| Popis: | Background: The aim of this study was to use whole body cardiovascular magnetic resonance imaging (WB CVMR) to assess the heart and arterial network in a single examination, so as to describe the burden of atherosclerosis and subclinical disease in participants with symptomatic single site vascular disease. Methods: 64 patients with a history of symptomatic single site vascular disease (38 coronary artery disease (CAD), 9 cerebrovascular disease, 17 peripheral arterial disease (PAD)) underwent whole body angiogram and cardiac MR in a 3 T scanner. The arterial tree was subdivided into 31 segments and each scored according to the degree of stenosis. From this a standardised atheroma score (SAS) was calculated. Cine and late gadolinium enhancement images of the left ventricle were obtained. Results: Asymptomatic atherosclerotic disease with greater than 50 % stenosis in arteries other than that responsible for their presenting complain was detected in 37 % of CAD, 33 % of cerebrovascular and 47 % of PAD patients. Unrecognised myocardial infarcts were observed in 29 % of PAD patients. SAS was significantly higher in PAD patients 24 (17.5-30.5) compared to CAD 4 (2-11.25) or cerebrovascular disease patients 6 (2-10) (ANCOVA p |
| Databáze: | OpenAIRE |
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